RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Stat3
RNA ID
RNA Type
mRNA
Alteration Pattern
dysregulation
Species
rattus norvegicus
Detection Methods
Immunofluorescence; qRT-PCR etc.
Target
Stat3
Pathway
NA
PubMed ID
Title
Arsenic trioxide prevents rat pulmonary fibrosis via miR-98 overexpression
Year
2014
Function
"MiR-98 decreased in the fibrotic lung tissues, while its target gene Stat3 was activated with PF development and the expression of Stat3 and p-Stat3 was significantly increased in BLM-induced PF. Arsenic trioxide prevented rat PF by up-regulation of miR-98 and inhibition of its downstream Stat3 signals."